B. Gillian Turgeon
Department of Plant Pathology
Ithaca, NY 14853
(607) 254-7458 (voice)
(607) 255-4471 (Fax)
Ph. D. University
of Dayton & C.F. Kettering Research Institute Yellow Springs,
M.S. Carleton University, Ottawa, Canada, 1971
A.B. / B.S. Carleton University, Ottawa, Canada , 1969
- 1996- Associate Professor,
Department of Plant Pathology, Cornell University
- 1995- Director, Center for Fungal Biology, Cornell University
- 1987-1996 Senior Research Associate, Department of Plant
Pathology, Cornell University
- 1984-1987 Research Associate, Department of Plant Pathology,
- 1982-1984 Postdoctoral Associate, Department of Plant Pathology,
- 1980-1982 Ph.D. Research Associate, C.F. Kettering Research
Laboratory, Yellow Springs, OH
- 1973-1976 Research Assistant, Laboratory of Dr. Norton Zinder,
Rockefeller University, NY
- 1972-1973 Research Assistant, Cell Biology Laboratory Co-ordinator,
- 1971-1972 Research Assistant, Department of Forestry, Environment
Research - 70%, Teaching - 30%
I have two major research
interests in the field of fungal biology- pathogenicity and mating
(reproduction). Both are complex developmental processes requiring
co-ordinated regulation of large numbers of genes and both involve
communication via signal transduction pathways. For pathogenicity,
the communication is between different organisms- the fungus and
its host. For mating, communication is between individuals of
the same organism. The long range goals of my research program
are to understand how fungi sense signals and respond to them,
and to identify sets of genes (and the functions of their products)
that are required for reproduction (both sexual and asexual) and
pathogenicity. I have pursued these goals with: (1) a genetically
well developed fungus whose features are appropriate for the questions
being asked, and (2) the most advanced genetic technology available
to dissect developmental pathways. The model fungus belongs to
the genus Cochliobolus; the technologies center on functional
genomics. The aim is to acquire as much sequence information as
possible and to perform functional tests (such as gene deletion)
coupled to appropriate assays for phenotype to prove or disprove
the role of a particular gene product in the developmental process
- PLPA738. Genetics and
development of filamentous fungi. , 2 credits, Fall, alternate
- American Phytopathological
- International Society for Plant-Microbe Interactions
- Mycological Society of America
- Genetics Society of America
- 1967-1968 Dr. Harry Katznelson
Memorial Scholarship, Carleton University 1967-1968 Francis C.
C. Lynch Scholarship, Carleton University 1969-1971 National
Research Council of Canada Post-graduate Scholarships
- 1998 Grant Proposal Review
Panel, NSF Microbial Genetics
- 1998 Co-Chair, Gordon Research Conference on Cellular and
- 1997- Associate Editor, Fungal Genetics and Biology
- 1996-98 Associate Editor, Molecular Plant-Microbe Interactions
1994- Editorial Board, Current Genetics 1989 Grant Proposal
Review Panel, Department of Energy
- Ad hoc reviewer for USDA/NRI, NSF grant programs
- Ad hoc reviewer for the journals Molecular and
General Genetics, Genetics,
- The Plant Cell, Molecular Plant-Microbe Interactions,
- Fungal Genetics and Biology, PNAS
- Department of Plant Pathology, Curriculum Committee
- Department of Plant Pathology, Chair, Mycology Curriculum
- Department of Plant Pathology, Special Lecture Committee
- Director, Cornell Center
for Fungal Biology
- Convenor, Fungal Biology Program Elements
- Yun, S.H., M.L. Berbee, O.C. Yoder and B.G. Turgeon. The
fungal self-fertile reproductive life style evolves from self-sterile
ancestors. Proc. Natl. Acad. Sci.
- In press
- Horwitz, B.A., A. Sharon, S.W. Lu, V. Ritter, T.M. Sandrock,
O.C. Yoder and B.G. Turgeon. 1998. A G protein alpha subunit
from Cochliobolus heterostrophus involved in mating and
appressorium formation. Fungal Genet. Biol.
- Kodama, M., M. Rose, O.C. Yoder and B.G. Turgeon. 1998. The
translocation-associated Tox1 locus of Cochliobolus
heterostrophus is two genetic elements on two different chromosomes.
- Christiansen, S.K., S. Wirsel, O.C. Yoder and B.G. Turgeon.
1998. The two Cochliobolus mating type genes are conserved
among species but one of them is missing in C. victoriae.
Mycol. Res. 102:919-929.
- Wirsel, S., B.A. Horwitz, K. Yamaguchi, O.C. Yoder and B.G.
Turgeon. 1998. Single mating type-specific genes and their 3'
UTRs control mating and fertility in Cochliobolus heterostrophus.
Mol. Gen. Genet. 259:272-281.
- Inoue, S., B.G. Turgeon, O.C. Yoder and J.R. Aist. 1998.
Role of fungal dynein in hyphal growth, microtubule organization,
spindle pole body motility and nuclear migration. J. Cell
- Inoue, S., O.C. Yoder, B.G. Turgeon and J.R. Aist. 1998.
A cytoplasmic dynein required for mitotic aster formation in
vivo. J. Cell Sci. 111:2607-2614.
- Wu, Q., T.M. Sandrock, B.G. Turgeon, O.C. Yoder, S.G. Wirsel
and J.R. Aist. 1998. A fungal kinesin required for organelle
motility, hyphal growth and morphogenesis. Mol. Biol. Cell
- Yun, S.H., B.G. Turgeon and O.C. Yoder. 1998. REMI-induced
mutants of Mycosphaerella zeae-maydis lacking the
polyketide PM-toxin are deficient in pathogenesis to corn. Physiol.
Mol. Plant Pathol. 52:53-66.
- Arie, T., S.K. Christiansen, O.C. Yoder and B.G. Turgeon.
1997. Efficient cloning of ascomycete mating type genes by PCR
amplification of the conserved MAT HMG box. Fungal
Genet. Biol. 21:118-130.
- Leubner-Metzger, G., B.A. Horwitz, O.C. Yoder and B.G. Turgeon.
1997. Transcripts at the mating type locus of Cochliobolus
heterostrophus. Mol. Gen. Genet. 256:661-673.
- Sharon, A., K. Yamaguchi, S.K. Christiansen, B.A. Horwitz,
O.C. Yoder and B.G. Turgeon. 1996. An asexual fungus has the
potential for sexual development. Mol. Gen. Genet. 251:60-68.
- Wirsel, S., B.G. Turgeon and O.C. Yoder. 1996. Deletion of
the Cochliobolus heterostrophus mating type (MAT)
locus promotes function of MAT transgenes. Curr. Genet.
- Yang, G., M.S. Rose, B.G. Turgeon and O.C. Yoder. 1996. A
polyketide synthase is required for fungal virulence and production
of the polyketide T-toxin. The Plant Cell 8:2139-2150.
- Yoder, O.C. and B.G. Turgeon. 1996. Molecular genetic evaluation
of fungal molecules for roles in pathogenesis to plants. J.
- Turgeon, B.G., M. Kodama, G. Yang, M.S. Rose, S.W. Lu and
O.C. Yoder. 1995. Function and chromosomal location of the Cochliobolus
heterostrophus Tox1 locus. Can. J. Bot. 73:S1071-S1076.
- Turgeon, B.G., A. Sharon, S. Wirsel, S.K. Christiansen, K.
Yamaguchi and O.C. Yoder. 1995. Structure and function of mating
type genes in Cochliobolus spp. and asexual fungi. Can.
J. Bot. 73:S788-S783.
- GuillÈn, A., B.G. Turgeon, P.R. Thorson, C.R. Bronson
and O.C. Yoder. 1994. Linkage among melanin biosynthetic mutations
in Cochliobolus heterostrophus. Fungal Genet. Newsl. 41:41-42.
- Lu, S.W., L. Lyngholm, G. Yang, C.R. Bronson, O.C. Yoder
and B.G. Turgeon. 1994. Tagged mutations at the Tox1 locus
of Cochliobolus heterostrophus using Restriction Enzyme
Mediated Integration. Proc. Natl. Acad. Sci. 91:12649-12653.
- Yang, G., B.G. Turgeon and O.C. Yoder. 1994. Toxin-deficient
mutants from a toxin-sensitive transformant of Cochliobolus
heterostrophus. Genetics 137:751-757.
- Mullin, P.G., B.G. Turgeon and O.C. Yoder. 1993. Complementation
of Cochliobolus heterostrophus trp- mutants produced by
gene replacement. Fungal Genet. Newsl. 40:51-53
- Turgeon, B.G., H. Bohlmann, L.M. Ciuffetti, S.K. Christiansen,
G. Yang, W. Schfer and O.C. Yoder. 1993. Cloning and analysis
of the mating type genes from Cochliobolus heterostrophus.
Mol. Gen. Genet. 238:270-284.
- Ciuffetti, L.M., O.C. Yoder and B.G. Turgeon. 1992. A microbiological
assay for host-specific fungal polyketide toxins. Fungal Genet.
- Straubinger, B., E. Straubinger, S. Wirsel, B.G. Turgeon
and O.C. Yoder. 1992. Versatile transformation vectors carrying
the bar gene of Streptomyces hygroscopicus. Fungal
Genet. Newsl. 39:82-83.
- Garber, R.C., B.G. Turgeon, E.U. Selker and O.C. Yoder. 1988.
Organization of ribosomal RNA genes in the fungus Cochliobolus
heterostrophus. Curr. Genet. 14: 573-582.
- Weltring, K., B.G. Turgeon, O.C. Yoder and H. D. VanEtten.
1988. Isolation of a phytoalexin-detoxification gene from the
plant pathogenic fungus Nectria haematacocca by expression
in Aspergillus nidulans. Gene: 68:335-344.